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Author Ramakrishnan, Venki, 1952- author.

Title Gene machine : the race to decipher the secrets of the ribosome / Venki Ramakrishnan.

Publication Info. New York : Basic Books, 2018.


Location Call No. Status
 GDL Central Library Non-Fiction    92 Ramakrishnan,V RAM    Available
1 copy being processed for GDL Central Library Non-Fiction.
Edition First U.S. edition.
Description xii, 271 pages : illustrations ; 25 cm
text rdacontent
unmediated rdamedia
volume rdacarrier
Bibliography Includes bibliographical references (pages 267-271) and index.
Summary "Everyone has heard of DNA--the molecule that seems to hold the secrets to all life. But by itself, DNA is little more than a blueprint for life, resting inertly within our cells. Hardly anyone, however, has heard of a ribosome. Ribosomes are enormous molecular machines, even more ancient than DNA, that translate the information in our genes into proteins. Those proteins in turn make up much of our bodies and catalyze thousands of processes within our cells. A ribosome, in short, is a machine no cell can do without. And until quite recently, how that machine worked was a mystery. [This book] is an insider account of the Nobel Prize-winning race to uncover the structure of this elusive molecule, told in two interlocking stories. One is a quest of fundamental biology to decipher the structure of the ribosome and show how it functions. This is no idle quest: the ribosome is the target of many major antibiotics, and its structure promises new treatments against deadly infections. The other story is the personal one, a portrait of scientists as human beings, driven as much by rivalry as by the desire to uncover nature's secrets. Ultimately, Gene Machine shows not just what it takes to win a Nobel Prize, but also reveals that who you know and how you handle them are just as important to scientific success as are brains, luck, and hard work."-- Dust jacket.
Contents An unexpected change of plans in America -- Stumbling into the ribosome -- Seeing the invisible -- The first crystals of the machine -- Going to the mecca of crystallography -- Emerging from the primordial mist -- A threshold is crossed -- The race begins -- Getting started in Utah -- A return to mecca -- Coming out of the closet -- Almost missing the boat -- The final assault -- Seeing the new continent -- The politics of recognition -- The ribosome road show -- The movie emerges -- The phone call in October -- A week in Stockholm -- Science marches on.
Subject Ramakrishnan, Venki, 1952-
Molecular biologists -- Biography.
Genetics -- Research -- History.
Genre/Form Autobiographies.
Other Editions: Reproduction of (manifestation): Ramakrishnan, Venki, 1952- Gene machine London, England : One World Publications, 2018 9781786074362
ISBN 9780465093366 (hardcover)
0465093361 (hardcover)

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