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Book Cover
Author Drlica, Karl.

Title Understanding DNA and gene cloning : a guide for the curious / Karl Drlica.

Imprint Hoboken, NJ : Wiley, c2004.


Location Call No. Status
 PAS Central Library Non-Fiction, 3rd Floor    576.5 DRL 2004    Available
Edition 4th ed.
Description xiv, 369 p. : ill. ; 23 cm.
Bibliography Includes bibliographical references (p. 325-335) and index.
Contents Preview: Life as interacting molecules -- PART I. BASIC MOLECULAR GENETICS -- Structure of DNA: two long, interwound chains -- Reproducing DNA: information transfer from one generation to the next -- Gene expression: cellular use of genetic information -- PART II. MANIPULATING DNA -- Microbial growth: one-celled organisms as tools for gene cloning -- Plasmids and phages: submicroscopic parasites used to deliver genes to cells -- Cutting and joining DNA: restriction endonucleases and ligases used to restructure DNA molecules -- Using complementary base pairing: hybridization, probes, and amplification using PCR -- Cloning genes: isolation of a hemoglobin gene -- Using cloned genes: gene structure, expression vectors, and gene function -- PART III. MODERN MOLECULAR GENETICS -- Beyond the central dogma: a sampling of insights derived from gene cloning -- Retroviruses: AIDS and gene delivery -- Cancer genes: the loss of growth control -- PART IV: HUMAN GENETICS -- Heredity: patterns of inheritance and genetic instability -- Application of human genetics: genetic testing, gene therapy, and DNA fingerprinting -- PART V. WHOLE GENOMES -- Genomics: using whole genomes to study life.
Subject Molecular cloning.
Recombinant DNA.
Genetic engineering.
Molecular cloning.
DNA, Recombinant.
Genetic engineering.
Molecular biology.
ISBN 0471434167 (pbk. : alk. paper)

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